Saturday, February 18, 2012

Steps Towards Making a Cure for Type One Diabetes | New Health ...


New Health And Fitness.Org - Health Information You Can Use

Type One Diabetes is genetically inherited, and therefore not something that you can immunise against, or change your lifestyle to cure. But that doesn?t mean that there aren?t ways in which scientists can look towards possible advances in treatment. There have already been significant leaps forward made in possible new ways of getting insulin into the bloodstream ? the main way of managing the disease ? such as automatic implants that measure blood sugar levels and apply drugs when necessary. And while there isn?t a ?cure? expected any time soon, there are steps being made towards understanding the disease better that might lead to a cure.

So what?s going on inside the body of a Type One sufferer? The problem comes down to an autoimmune response ? so the body attacking itself basically. White blood cells which usually help mop up bacteria, called B cells, register the cells of the pancreas which produce insulin as a problem. As a result they are broken down, and are rendered ineffective in the production of insulin. We need insulin because this is the body?s chemical message to tell cells to stop taking more sugar into the blood.

One approach is to study the interaction of B cells with the pancreas to figure out why they trigger a response in the immune system. A team at King?s College London are currently investigating a specific molecule on the pancreatic cells of Type One sufferers, called HLA molecules, which seem to cause the body to think there?s a problem. If this work can figure out a way of restricting the action of the B cells on these HLA molecules, it might just lead to a cure.

The University of Cardiff School of Medicine is carrying out a study on the other half of the equation ? the B cells that lead the attack. By building up an idea of what makes all aspects of this condition work the way they do, the hope is that scientists can pin down ways of restricting the harmful actions of the immune system.

With any of these approaches, a lot of money and hard work is required to make progress, and although there have been successes there?s still a lot to do to find cures.

Find more information on diabetes UK. Just search online.

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Source: http://newhealthandfitness.org/2012/02/17/steps-towards-making-a-cure-for-type-one-diabetes/

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