kathyburkeyx: May 2012

Thursday, May 31, 2012

Four Cancer Therapies to Watch | OneMedPlace - Sentinel

Written by Lara Morrow on May 31, 2012

On June 1, more than 25,000 cancer specialists will come together at the 2012 American Society of Clinical Oncology Annual Meeting in Chicago. Thousands of scientific abstracts will be released, and just as many investors will gather in hopes of finding the next big thing. With ASCO hours away, we look at some small biotech companies making headway in cancer treatment.

Celsion [NAS: CLSN] is a small medical device-turned-oncology drug development company focusing on delivering high concentrations of known chemotherapeutics to the lesion site. The company?s lead candidate, ThermoDox?, is a heat-activated liposomal formulation of the chemotherapeutic drug doxorubicin. The treatment delivers doxorubicin to the cancer cells that have survived radio frequency ablation of the tumor. In addition to a more efficient delivery, the company believes ThermoDox has the potential to reduce drug exposure distant to the tumor site and thus limit associated side effects. In 2009, the US FDA granted Orphan Drug designation to ThermoDox, and in 2010 granted Fast Track Designation.

Celsion is conducting a Phase III trial for primary liver cancer, a Phase II trial for liver metastases, and a Phase II trial for breast cancer. If ThermoDox is approved for liver cancer by 2013, projected annual revenues (based on a fraction of the radiofrequency ablation market share alone) are expected to reach $230M in 2014, According to Seeking Alpha. A successful demonstration in primary liver cancer could lead to great success in other cancers.

CLSN declined to a low of $1.63 in December 2011 and stayed below $2 until this month. Seeking Alpha notes that 6 insiders have been constantly buying back shares since December 2011, which the financial blog believes is a strong indicator of the stock?s undervaluation.

Celsion has a market cap of $61.47M. After a mid-March low at $1.65, the stock is currently hovering at $1.90.

Del Mar Pharmaceuticals is a private company developing new drug candidates targeting orphan cancer indications representing market opportunities in the potentially billions of dollars worldwide.? The company aims to develop products that will have a high impact in patient care and a high return for investors.

The United States FDA Office of Orphan Products Development has granted orphan drug designation for VAL-083 for the treatment of glioma, including glioblastoma multiforme (GBM), the most common and aggressive form of brain cancer. The company?s lead product, VAL-083, is a well-studied chemotherapeutic for patients with Glioblastoma. Published pre-clinical and clinical data suggest that VAL-083 may be active against a range of tumor types via a novel mechanism of action.? Glioblastoma (GBM) remains one of the most difficult tumors to treat first because many new agents fail to cross the blood brain barrier (BBB), and second due to intrinsic drug resistance.? VAL-083? readily crosses the BBB and is currently undergoing human clinical trials in the USA in refractory GBM patients.

Northwest Biotherapeutics [OTC: NWBO] is another small biotech company focused on developing immunotherapy products to treat cancers. One month ago, NW Bio made a joint announcement with the Fraunhofer IZI Institute that their 13-month collaborative efforts have resulted in the completion of ?significant milestones? in NW Bio?s DCVax?-L program for brain cancer in Germany, leaving the company positioned to move forward with the manufacturing process for DCVax?-L. The company has? completed and filed all necessary documentation and applications as part of the regulatory process.? The parties are now awaiting the final inspection required before the manufacturing authorization can be granted and manufacturing can proceed for clinical trials and hospital exemption cases. The inspection is scheduled for June 2012.

NW Bio has a market cap of $40.24M. After sitting at a per-share price of next to nothing for most of April, stocks rose to almost $.35 per share by the end of the month, and now sit around $.25.

Galena [NAS: GALE] is a company conducting the PRESENT (Prevention of Recurrence in Early-Stage, Node-Positive Breast Cancer with Low to Intermediate HER2 Expression with NeuVax Treatment) study, which is a randomized, multicenter, multinational clinical trial that will enroll approximately 700 breast cancer patients. The PRESENT study was initiated January 20, 2012, and the study?s primary endpoint is 36 month Disease Free Survival. On March 20, 2012, Galena was granted a patent that covers the use of NeuVax for treating certain breast cancer patients who have achieved remission with their current standard of care, but have no available HER2-targeted adjuvant treatment options to maintain their disease-free status. The patent provides exclusivity for this indication until 2028. If the vaccine works in that lower level of HER2-Negative group, then Galena can go look at other cancers that come from an epithelial cell, which are the big cancers like lung cancer, prostate cancer, colon cancer, some blood cancers, ovarian cancer, and gastric cancer. The vaccine has already been tested in prostate cancer. Galena is also currently testing its Folate Binding Protein (E39) in ovarian and endometrial cancer. The company?s candidates have the potential to treat several other cancer types, including both lung and colon. Galena also has approximately $25 million in cash as of April 30, thanks to additional funding from company?s April financing and the recent exercises of a majority of outstanding warrants.

Galena has a market cap of $65.05M. Stocks peaked with the March announcement at $2.75 per share, and now sit around $1.50.

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The Benefits of Article Marketing for Your Business | Insider Secrets ...

Article marketing has proven to be an effective way to promote your online business for a number of reasons. They are the equivalent of infomercials on the TV, giving both interesting factual information and promoting products and services that can help solve a particular problem.

In addition, article marketing can drive traffic to your site, help you get subscribers for your newsletter, and help you improve your page ranking with certain search engines. Links back to your site or products from other sites can be perceived by Google as a vote for your site, indicating that it is interesting and relevant to a particular keyword.

Article marketing is the use of factual articles on niche topics to help drive traffic to your own site. Rather than a pure promotional piece, these articles will contain high-quality information and leave the reader eager for more. On the top article directories such as Ezinearticles, your content will appear attractively and at the end of the article you will be allowed to give promotional data about yourself in the form of a resource box.

In your resource box you would put a brief biography of yourself and your contact information, including a link over to your site.

Article marketing has become a popular way to spread the word about your business in a non-spammy way on a wide variety of sites around the Internet. It has also been used to boost the rank of a site in the eyes of search engines like Google, though with the April 2012 Google update, these links are not only valued less highly, but can even be penalized under the Penguin algorithm update. (See Joan Mullally?s guide on 44 Marketing Trends in 2012 for more information.)

The more articles you put into the directory, the better will your site?s search results will be because the site will be considered to be more relevant. Sites at the top of Google?s search engine results pages will get more natural traffic, also termed organic traffic, that is, traffic that is not paid for, as compared with Pay Per Click (PPC) traffic.

Some article directories have gained a reputation for publishing rubbish, but there are still some reputable ones that will help add to your online presence. Look at it this way. If someone uses those sites regularly and types in dog training, you have a better chance of being found and ranking highly on the article directory for that key phrase than you do on Google.

If visitors then like what they read and click to find out more about you, you have the potential for a repeat visitor and perhaps even subscriber and customer.

Some people advocate publishing an incomplete article to force people to come to your site, but this seems fairly obvious as a marketing ploy and can be frustrating for the reader.

Other Internet marketers offer good articles off site at the directories but lead them to a rubbish site full of ads with the express goal of getting ad revenue from the clicks they get on the ads and banners they have put up all over the site. This is a valid way of making money, but certainly not loyal repeat visitors, which we feel are the life-blood of any long-term, sustainable online business.

Still other sites are publishing articles which are incomplete and poorly written in an effort to get as many up as possible for the sake of the links and the page rankings. The recent changes to the Google Panda update that first hit in Feb 2011 and has now hit online business owners in April 2012 can actually trigger a site review by a human being. If your site fails, you can end up in a penalty box for 3 to 6 months, which would cause the traffic at most sites to plummet.

The trend towards article marketing has also led to a lot of copied content or rephrased content, which we commonly refer to as spun content. Content spinning through software or human means was designed to help business owners rank highly for as many keywords as possible related to the niche they were working in.

With the recent Google changes, duplicate content and keyword stuffing in poorly written articles generated by a computer will also get you penalized if you are not careful.

Article marketing is not dead, but it is certainly in need of an overhaul in 2012. If you have been cranking out a lot of poor-quality articles, slow down and let your quality start to come through. Do not try to take short cuts. After all, the content that you produce is a reflection of the information products that you are trying to sell online. If you see all of your content on your site and article directories as a free sample of what people can look forward to if they buy your product, you might be able to make more sales of your products.

At the very least, you can start to position yourself as a knowledgeable expert on your niche without being seen as a spammer. Combined with other search engine optimization techniques, article marketing done correctly can still be a valuable source of traffic to your site and a measure of relevance and therefore rank so long as you know what Google is looking for, and what they are penalizing.

FURTHER READING
SEO Success Secrets: How to Master Search Engine Optimization Techniques for Continuous Free Traffic to Your Website

44 Top Online Marketing Trends in 2012: How to Use Them to Increase Your Profits

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Analysis: Syria massacre pushes Moscow toward decision point

MOSCOW (Reuters) - Vladimir Putin resumed the Russian presidency declaring a moral right to promote Kremlin power on the world stage. A massacre in Syria could now press him towards abandoning his closest Middle Eastern ally, but any backdown would have to be carefully engineered to protect Russian interests and save face.

International envoy Kofi Annan said the massacre of 108 people, half of them children, in the town of Houla showed Syria at a 'tipping point'. He urged President Bashar al-Assad to halt the killing that the West blames squarely on his troops.

"I think there may be changes in Russia's position, because Russia has lost its ability to manage the situation," said Fyodor Lukyanov, editor of the journal Russia in Global Affairs and a foreign policy expert with Kremlin connections.

With Western and Arab League pressure on both Syria and Russia after the Houla killings, he said, a Russian shift "is more likely than before - but there is no decision yet."

Foreign Minister Sergei Lavrov, speaking after talks with British foreign minister William Hague, blamed both sides, government and rebels, for the Houla massacre; but he appeared to move a degree towards Western and Arab League positions in acknowledging Assad bears overall responsibility for security.

Putin flies to Berlin and Paris this week for talks he had hoped would be led by economic projects to modernize Russian industry. German Chancellor Angela Merkel and French President Francois Hollande may have other ideas.

"He did not want to talk about Syria, where Russian influence is overestimated," said German political scientist Alexander Rahr. "If the West decides Putin is defending Assad, that will spoil his chances to develop partnership with Germany and France, which are very important for him."

Russia has helped Assad play for time through more than a year of bloodshed in which the United Nations says government forces have killed more than 9,000 civilians. The government says thousands of police have been killed by 'terrorists'.

Putin spokesman Dmitry Peskov told Reuters nobody had "unambiguous information" about Houla. "One should not give in to emotion at such an important moment."

"Russia is a country with a consistent foreign policy and pressure is hardly appropriate."

HOMS

With China, Russia vetoed two Western-backed Security Council resolutions condemning the government, including one in February that backed an Arab League call for Assad to cede power.

The context of that veto might suggest a Russia inured to such atrocities or at least strongly wedded to the idea that Assad's forces were no more to blame than 'terrorist' rebels for the violence. The vote came shortly after hundreds of people were reported killed by government shelling of the city of Homs.

Houla, however, is arguably different.

The massacre took place with United Nations monitors present in the country. Details emerged quickly and in graphic form. The U.N. said whole families had been shot dead in their homes while houses suffered intense artillery bombardment.

Photographs of the bodies of children appeared on the front pages of newspapers across the Western world. In Russia, the coverage of the massacre was less prominent.

Wednesday's Komsomolskaya Pravda, a mass circulation newspaper that has been used to shape public opinion, carried a picture of a blue-helmeted UN observer and a line of bodies wrapped in sheets, the head and chest of one boy visible.

"The West has begun war in Syria with the Belgrade bombing scenario", the headline read, in reference to the 1999 NATO bombing of Belgrade intended to stop Serbian action against the breakaway province of Kosovo.

The story suggested the West was using the Houla massacre as a pretext for military intervention in Syria. Kommersant and Izvestia newspapers, however, allowed that Russia was now under stronger pressure to change its stance.

The diplomatic pressure to help press Assad to go, or to engineer his exit, could move Moscow from its policy of awaiting an ebbing of the violence.

"I think we're beyond this point now, we've passed this point with the massacre," said Vladimir Frolov, a Kremlin-connected foreign policy expert and president of LEFF Group, a Moscow-based government relations firm.

Moscow has stepped up criticism of Assad and courted his opponents, suggesting it is hedging its bets and hopes to preserve influence in Syria if he is forced out.

The Kremlin, however, does not want to lose its firmest foothold in the Middle East - a client for billions of dollars' worth of weapons and the host of Russia's only warm-water naval port outside the former Soviet Union.

Nor does it want to look weak, having paid the price for weakness in the immediate aftermath of the disintegration of the Soviet Union when it surrendered one foothold after another from eastern Europe to the Caribbean, Africa and Asia.

Putin, flanked by military commanders, set out his vision of a powerful Russia during World War Two Victory Day celebrations this month, two days after resuming the presidency.

"Russia consistently follows a policy of strengthening global security and we have a great moral right to stand up determinedly for our positions because our country suffered the blow of Nazism," he declared, flanked by his military commanders in front of the redbrick walls of the Kremlin.

He said the lessons of the war remain valid and that "respect for state sovereignty" is a crucial guarantee it will not be repeated - a warning against Western efforts to promote "regime change".

CONTROLLED DEMOLITION

Russian sensitivities run deep and suspicions of a Western-led diplomatic 'ambush' will be hard to overcome.

Putin made clear he was incensed when NATO, given the green light for air operations in Libya last year when Russia refrained from vetoing Security Council authorization, helped rebels oust longtime leader Muammar Gaddafi.

Since enraging the West with its Syria veto in February, Russia has strongly backed U.N.-Arab League envoy Kofi Annan's peace plan, which is acceptable to Moscow because it includes no direct call for Assad to leave power.

Russia has long contended that it supports the peace plan, not Assad, and would accept a political transition as long as it is a product of an internal Syrian political process free of conditions dictated from outside.

Meanwhile, analysts say, Russia is watching Syria closely, trying to determine whether Assad can hold onto power and worrying there may be a point when helping him stay there is not worth the sacrifice of global prestige.

Earlier this month, U.S. President Barack Obama told G8 leaders including Russian Prime Minister Dmitry Medvedev that Assad must leave power and pointed to Yemen as a model of how political transition could work in Syria.

In Yemen, Frolov said, Saudi Arabia "pressured both the opposition and the government to agree on a formula for the political transition.

"I think that's what Moscow is trying to achieve in Syria, but I'm afraid Assad is denying Moscow this opportunity," he said.

Georgy Mirsky, of Moscow's Institute of World Economy and International Relations, said the evidence forced Russia to acknowledge government involvement in the Houla massacre, but that it is far from giving up on Assad.

"It would be a mistake to see ... a signal that Russia is beginning to distance itself from Assad, because Assad has not lost the war yet," he said.

But whether or not Russia is amenable, the limits of its sway over Syria could be the biggest hurdle to a deal for Assad's removal. Russia does not have the same influence in Syria that Saudi Arabia used to force Yemen's president to go. Yemen relies on Saudi Arabia for billions of dollars of aid.

"Russia cannot tell Assad to get out. Even if we did, it does not mean that he would - we're not in that type of relationship," Frolov said. "Russia can give him advice and nudge him to do this, but ultimately he makes his own decisions."

There are plenty of other obstacles to make Moscow wary of backing such an arrangement.

"There is a lot of talk about the Yemeni scenario. It won't work - it's a non-starter, because in Yemen there was a horrible split within the governing elite - nothing of this kind has been happening so far in Damascus."

Syria's governing elite "is well aware that as soon as Assad goes, it will mean the beginning of the end for the whole elite - the whole bloody building will come crashing down," he said.

Russia may take some persuading it could salvage more from the chaos of an Assad exit than the continued stalemate which keeps Russia's base open and its commerce, including arms trade, active. More Houlas could follow. Moscow could consider the potential loss to its international image ultimately too great.

Putin could be lured by the prospect of a controlled demolition, a peaceful exit by Assad, carefully orchestrated, that can be presented as the work of the Syrian people alone, with perhaps the final solicitations of Moscow.

"Many in Russia understand that Assad has no political future," Lukyanov said. "If Russia can help him not be overthrown but leave smoothly, this can certainly be sold as a success."

(Additional reporting by Gleb Bryanski; editing by Ralph Boulton and Janet McBride)

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Wednesday, May 30, 2012

The Simplistic Professional Stomps All Over Real Estate Marketing ...

What defines you as a professional? What role does your peer group play in that definition? Does it translate to your current job description?

Welcome to a new series of articles from the team at Ardynn Publishing revolving around the act of being a ?Simplistic Professional?. The idea came into being after recognizing an industry wide trend reversal where everything become simplified. From technology and marketing strategies to personal look projected by today?s real estate professional. Talk about the perfect way to start the new year, the idea seemed to hit us from every angle all at once. It was prevalent at Inman News? Real Estate Connect NYC and coming out of REAL Trends the same week.

So I decided that we would sit back and see how things transpired for a few oaths, gauge the results and step in to fill in the holes in order to give REALTORS a complete concept to live by. As always, the first place our team looks for answers that need a general pool of professional feedback is LinkedIn. An we posed the above question with some dated, and some surprising answers.

Take a look at what some had to say defines them as a professional.

This was selected as Best Answer

I am a professional these are the things I do every day on or off the job.

A professional learns every aspect of the job. An amateur skips the learning process whenever possible.

A professional carefully discovers what is needed and wanted. An amateur assumes what others need and want.

A professional looks, speaks and dresses like a professional. An amateur is sloppy in appearance and speech.

A professional keeps his or her work area clean and orderly. An amateur has a messy, confused or dirty work area.

A professional is focused and clear-headed. An amateur is confused and distracted.

A professional does not let mistakes slide by. An amateur ignores or hides mistakes.

A professional jumps into difficult assignments. An amateur tries to get out of difficult work.

A professional completes projects as soon as possible. An amateur is surrounded by unfinished work piled on top of unfinished work.

A professional remains level-headed and optimistic. An amateur gets upset and assumes the worst.

A professional handles money and accounts very carefully. An amateur is sloppy with money or accounts.

A professional faces up to other people?s upsets and problems. An amateur avoids others? problems.

A professional uses higher emotional tones: Enthusiasm, cheerfulness, interest, contentment. An amateur uses lower emotional tones: anger, hostility, resentment, fear, victim.

A professional persists until the objective is achieved. An amateur gives up at the first opportunity.

A professional produces more than expected. An amateur produces just enough to get by.

A professional produces a high-quality product or service. An amateur produces a medium-to-low quality product or service.

A professional earns high pay. An amateur earns low pay and feels it?s unfair.

A professional has a promising future. An amateur has an uncertain future.
from David Velasquez

I came across a definition of ?professional? many years ago by Bob Johnson in a sales course, and have used it several times since. A professional is one who can always be relied upon to do the right thing in any given situation without conscious forethought or effort. I like this definition, as to me it sums up what being a professional is all about.
from Judy Hojel

A desire to learn and to grow; a willingness to listen and to participate in a team, even when my ideas are not accepted; and a passion to do my part to help communities improve their socioeconomic and cultural offerings are some of the qualities that describe me as a professional. I have several peer groups, both in the public policy world and in my visual arts world and they help me to see more than I could/would on my own. I think these qualities and ways of being translate to what I do in both professionals and, actually, being an artist and being a drafter of public policy are not all that different. Successful artists and good policy requires creativity and thinking outside the box.

Links:

http://www.christinegoldbeck.com

http://www.artsonunion.com

from Christine Goldbeck

The ability to provide what I say I can provide to my clients?

What role does your peer group play in that definition?
In the sense that I get sub contracted out by other event planners?

Does it translate to your current job description?
Yes it does?

You are a professional when you get paid to do it.

from Lee Schlesinger

if you get paid you are a professional. if you mean acting in a ?professional? manner then its something which will come down to personal taste. and in that case professional is usually a euphemism for ?like me? and unprofessional is a euphemism for ?not like me?
from Bruce Eberhardt

Being a professional is having ethics while delivering the promised services or products while being paid for it.
A professional conduct themselves with integrity. Wikipedia defines a professional as a person who is paid to undertake a specialised set of tasks and to complete them for a fee.

The main criteria for professional include the following:
Expert and specialized knowledge in field which one is practicing professionally.
Excellent manual/practical and literary skills in relation to profession.
High quality work in (examples): creations, products, services, presentations, consultancy, primary/other research, administrative, marketing, photography or other work endeavours.
A high standard of professional ethics, behaviour and work activities while carrying out one?s profession (as an employee, self-employed person, career, enterprise, business, company, or partnership/ associate/ colleague, etc.). The professional owes a higher duty to a client, often a privilege of confidentiality, as well as a duty not to abandon the client just because he or she may not be able to pay or remunerate the professional. Often the professional is required to put the interest of the client ahead of his own interests.

Reasonable work morale and motivation. Having interest and desire to do a job well as holding positive attitude towards the profession are important elements in attaining a high level of professionalism.

Participating for gain or livelihood in an activity or field of endeavour often engaged in by amateurs b : having a particular profession as a permanent career c : engaged in by persons receiving financial return

Appropriate treatment of relationships with colleagues. Consideration should be shown to elderly, junior or inexperienced colleagues, as well as those with special needs. An example must be set to perpetuate the attitude of one?s business without doing it harm.

A professional is an expert who is master in a specific field.

Links:

http://www.saharconsulting.com/bio.aspx

from Sahar Andrade

You are a knowledge worker and if you are paid you are professional
from Brijendra Chaudhary

Being a professional entails the interest, education and drive to excel in your chosen profession. It doesn?t matter if it?s sales, IT, or being a call center phone rep, we do what it takes to be the best we can be. And we improve our craft every day. That?s being a professional.

Those people around me know what I do and know that I do it well. I am identified for the most part by my profession and I hope exemplify the best qualities of my profession.
from Ronald Rook

There?s an interesting difference between the use of the word professional as a descriptor and in conversation. The descriptor is straightforward enough, but in conversation, I have often heard it used to kill a conversation short, as in ?I know better, do it my way?. I generally prefer the word competent over professional as it seems both more neutral and more accurate. I?m not saying that the word professional is a wrong one per se, just that first-hand I?ve heard it used to cover or promote BS so many times that the association sticks, at least for me.
from Martin Roche

I believe that Judy?s and Martin?s answers go in the same direction, being the use of the word ?competent? very adequate here. A person is not a professional not only because of the fact that they are paid, but also because they are competent to solve specific problems.

And the peer group plays a crucial role when it comes to motivation. Actually there are at least 2 motivational aspects within a copany?s staff: competition and shared knowledge. In other words at the same point one can be motivated by trying to be better than others and also by learning with others. Note that I?m not mentioning that one needs to trample over others to get what they want because obviously this is not professionalism.
from Mateus Fonseca Pereira

I took a long road to develop a value system that includes things other than career advancement and financial success. After 30 years of chasing superficial reality in the form of money, material, travel and status, I found there are other values far more fulfilling.

It was a journey that brought me to a legacy of contribution without salary, volunteering without expecting a return, unconditional giving and receiving the gratitude, and respect of many small enterprises through my volunteer work.

It offers a unique opportunity to help start-ups and small business, enabling me to stay involved in my fields and assist in growing success stories.

The challenges are unending, the satisfaction is high and the opportunity to contribute and pass one?s knowledge forward is unlimited.
from Kenneth Larson

As you can see, many different view points can lead to the same road. It seems to mainly come down to how you live your life, value your contribution to society and the expectations you seek from your peers, clients and the world at large. I personally believe you need to be extremely knowledgable, show a willingness to share that knowledge not matter the revenue return and maintain the mindset that it takes constant work to stay professional. ? Michael Harris-Arzon

In the coming weeks The LIME Magazine will be offering a series of articles the moves beyond the definition to a road map you can follow as you strive to become and/or stay A SIMPLISTIC PROFESSIONAL.

COMING TOPICS
Revamping your personal image

Building an online presence so sophisticated, yet oh so simple that it takes five minutes a day

Creating lasting relationships with the simplest of messages

Let technology do the big things while you keep your life simple

Simple PR with 3 clicks of the mouse

?..and more surprises to blow your mind. So stay tuned as we stomp all over what you have always known as good marketing for your real estate brand

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What Affect Does Debt Consolidation Have on Taxes?

Do you have huge outstanding debts that you need to pay off? Are you finding it difficult to make the debt payments on your own?

If yes, you may choose debt consolidation to get rid of debt problems. Debt consolidation enables you to merge your multiple debts into one so that you can make a single monthly payment on all your outstanding debts. On enrolling with this program, the debt expert negotiates with your creditors and requests them to reduce the interest rate on your outstanding debts, thus making the debt payments affordable for you. Thus, you pay off your debts within a specific time period and become debt free.

You may also pay off the other loans by taking out a consolidation loan. These loans are offered by the banks and the financial institutions. Once you pay off your other loans with this loan, make sure you repay your new loan. There are two types of consolidation loans ? secured and unsecured. Secured loans are those which you take out by keeping your house or property as collateral. You pay low interest rate when you take out a secured loan. Unsecured loan is the one which you can take out without keeping anything as security against the borrowed amount. This loan is a sort of risk for the lender as the borrower does not keep anything as security against the loan. You may find it difficult to take out unsecured loan if your credit score is not good.

You may take out a home equity loan for improving your house or property. However, these days many people are using their money for accomplishing various goals. Home equity line of credit, also called HELOC, can be selected to finance anything like buying a boat, paying off the credit card debts or loans. One of the main advantages of it is the tax benefit. Since home equity line of credit is tax deductible, so even if the interest rate is same as that of a credit card, the consequence seems to be helpful. The only way to know your situation is to carry out the necessary calculations. You may use an online loan calculator that will help you do the calculations correctly.

It is possible to take out a loan and make the payments for the medical costs. You must be aware that a good number of people pay their medical expenses by using their credit cards. This seems to be the most costly method since a large percentage of the interest on such loans and the medical costs are tax deductible. The interest that you pay on the student loans is tax deductible. Your situation may be different from someone else?s and so, using a tax filing software is certainly the best way to calculate the pros and cons for your case.

Whatever may be the scene or whenever you're thinking to take on debt particularly for a considerable amount, take time to be familiar with the tax implications. This may save you significant amount of cash that can be of great value to you.

Marlon Powell is a financial writer who deals with financial articles and blog posts. He loves to share his knowledge on finance with the readers and contributes his articles to various communities, websites and blogs. Some articles covered by him are on IRS tax debt, best way to consolidate credit card debt, the consequences of taking out payday loans and tips for the prospective business owners.

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Tuesday, May 29, 2012

The Importance Of Having A Trademark Attorney - CareCrunch ...

It is but bizarre to find massive businesses having their personal lawyers. Being ignorant of the regulation is not an excuse for not with the ability to sue or to be sued. That is why if your corporation is slowly climbing the steps of success, you?d higher rent an attorney.

Do you know probably the most important asset that your enterprise can personal? Well, the answer could be very simple. Trademark is a crucial asset that will distinguish your corporation from different opponents and stand out within the market. Just remember to have a great one because having a not-so-good trademark can blunt all your advertising efforts and entangle your business in legal disputes.

If you don?t have a registered trademark, fill out an software form now and file it online. While you?re in the interim, you should use SM or TM to let other people and companies know that you intend to make use of such mark as soon as your software is approved.

From the very start, you want an attorney. He or she might help you determine the enterprise entity that you want to enter, and guide you through the method of beginning it. All legal issues and necessities like permits and licenses are dealt with by your legal professional, so you may be confident that you?re doing a legal business. Probably the most essential causes of getting an legal professional is that you will want his or her experience when you file for a trademark registration.

In accordance with the trademark regulation, the bottom line is to be first in the usage of such mark. Imagine conducting a business for quite a while with out a registered trademark. After which someday, a bigger company moves into your native space which used the identical mark or identify within the interstate commerce ahead of you. If this is the state of affairs, you can be compelled to vary your signage and your goodwill shall be disrupted together together with your model name. Your credibility might be in query and your clients will be confused. And that is all due to not having a registered trademark.

It isn?t laborious to get a registered trademark, particularly when you?ve got a trademark legal professional to handle the varied obligations including:

- advising on selection and adoption of latest and original trademarks ? submitting applications for a registered trademark ? prosecuting purposes ? advising on trademark registrations and its use ? handling trademark revocations, oppositions, assignments, and invalidations ? advising on matters of trademark infringement

Emblems fall underneath the regulation on intellectual property, and for those who?re planning to acquire a trademark, it would be greatest to consult a competent trademark attorney. He or she is the correct individual that can assist you in making a proper trademark application.

Make sure that you find an lawyer that?s right on your situation. Having your personal trademark attorney will give your trademark software an edge over other applications as a result of greater than anybody else, your legal professional has far-reaching data of the procedures and the trademark law. Your legal professional can provde the proper advice on the features of trademark submitting and services.

When selecting your trademark slogan or product title, guantee that your legal professional is with you. He would doubtless recommend getting a trademark report first. By looking the internet and the positioning of USPTO, you may obtain a report of current trademarks. If in case you have questions about the cost of registering emblems and the registration procedures, your legal professional can counsel you on such matters.

If in case you have your trademark lawyer, you may handle virtually any scenario together with conditions that of receiving particular letters like a stop and desist. This happens when one other occasion believes that you?ve got infringed their trademark. With an attorney, you can get the appropriate assistance.

That?s the reason it is advisable to be very careful in choosing your trademark attorney. Don?t simply pick any really helpful attorney from an advertising or referral service. Chances are high these individuals usually are not that capable, with little data and experience. This is also true within the case of advertising, where most of the lawyers provide impersonal services and so they run their companies like factories. Choose an lawyer that offers particular person attention to trademark matters, licensed or registered, and observes professional ethics. If you can find one with all of the qualifications and qualities, then you possibly can anticipate that your trademark application will surely be approved.

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Online Digital Marketing ? The In-thing For Today's Business ...

May 28, 2012 (Powerhomebiz.com) In today?s world everything has become commercialized, including the brand promotional activities. People don?t use traditional methods anymore to gather or spread information. Online Digital Marketing has taken place over conventional methods in which businesses are promoted through internet and mobiles respectively.

digitalmarketing People have a long way to gather information through internet or other forms of media and make their decisions accordingly. More and more consumers are getting connected online and taking a cue from their colleagues, peers, and other networks, as well as from experts they don?t know personally. Basically all this promotional activities of today are creating an on-line community of people with same interest. As a result businesses are promoting their brands through digital media and capturing the interests of online audiences.

The extensive product promotion is also done through numerous micro sites, podcasts or video marketing. Basically after lot of research and study that the marketing experts devise unique strategies that will attract consumers online at an affordable rate, as well as producing excellent results.

Role played by the Social Media:
Social Media Marketing plays an important role in today?s world for online digital marketing. Every network agency is desperate to attract customers these days with the help of Facebook, Twitter, Youtube, etc. As a matter of fact lot of interaction is taking place between the consumers and owners these days? via media and internet. Business is not only about transaction these days but lot of interaction is involved.

But to carry out effective marketing online is very tricky. With so many companies vying for consumer?s attention and going out of their way to convince people to visit their site and buy the products. To improve their digital marketing services, certain guidelines should be implemented.

Knowing the target audience: This is the vital element for promoting any business; the businesses should understand whom they are targeting whether it?s an adult, child or women. The brand should be able to attract people properly.

Setting of Goals: Understanding and setting of goals is also very important. The companies should think beyond simple sales and marketing, while promoting their products in the media.

Being Creative: Creativity is as important as getting up in the morning to start the day. The businesses should think about different ways to attract potential consumers, as well as stay connected to the existing ones. There should be rewards for users who can suggest their friends, peers, and relatives about the certain product. In some way or others the users will help the company to remain a part of their life.

Sharing Content: This is very important to social media marketing; the audience should be able to share the content they like across various platforms; this will include several buttons that will encourage sharing. With the help of sharing the consumer can press ?Like? or ?Tweet? about a particular promotional offer, which can be shared effectively by their peers and friends.

It?s expected that the social media marketing and promotional activities will expand by leaps & bounds over the years, resulting in the leading of business, sales, as well as brand preferences.

For More Information you can visit this website: http://www.gatewaytechnolabs.com/

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Trouble at Greenpeace nuclear protest in S. Africa

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Monday, May 28, 2012

A Profitable Internet Marketing Business Calls for The Appropriate ...

Posted May 27th, 2012 by Ziggy & filed under Medicine.

You Can Profit From Doing Internet Marketing With The Correct System

A lot more people are considering setting up a home-based business. Obtaining a well-thought-of system for doing online marketing is one of the best ways of generating money at home. Before you get overly excited about your online business, you have to learn of the drawbacks you will face. Having an internet business certainly has many satisfying sides, but there are also negative ones and you need to make an effort to find out about both. If you do this, it?s going to save you plenty of trouble down the road. Goji Berry Advance

The internet is nothing but a tool, and like all tools, it has to be properly used for it to be useful in operating an online business. Individuals are not at all times realistic with regards to the Internet. Quite a few consider it as a divine solution that can only give rise to miraculous results. Yet another group of folks distrust the internet completely, thinking it to be filled with fraud and lies. The reality is somewhere in between. Given a high quality, proven, marketing system and a good measure of time and effort, expecting to establish a significant business wouldn?t be improbable. You have been told that your potential customers come from the whole world, but so do your competition. You need your business to be in a market of the market where the competition is minimal. Hoodia Balance

Among the best things about a business on the internet, is that it will always be open. If you have a niche website that you?re comfortable with, as soon as everything is set up, you can be making sales daily, throughout the whole day. Since the web is world-wide and across all time-zones it?s always busy. Your business can therefore be busy all of the time, too, and make more sales. Once you put an opt-in box on your website, you can build a list of customers with little expense. As soon as you get their contact information, you can send them helpful information, together with advertisements for products that you are trying to market.

The fact that you don?t have any personal interaction with your customers is a huge drawback. Lots of people make a buying decision depending on the discussion they have with a sales rep. People often would like to hear a personal endorsement. You can?t provide anything personally if your business is online. The best you are able to do is treat individuals well through your messages. That?s good enough for some individuals, but unfortunately there are a lot more people who don?t purchase anything on the internet. Have an in-depth look at your web site?s visitor profile, and determine the odds that they are going to buy something.

In case you?ve got an offline business, it is sensible to increase your business by using an online marketing system. We all are different in how we do things, and we won?t enjoy equal success from adding a web site to our business. Nevertheless, if it is done correctly, creating a website will inevitably be good for your business.

Review: Salt & Straw - - Portland Food and Drink - odugutumad's ...

Salt & Straw Ice Cream When I was growing up, on hot summer days dad used to get everyone into the car and head out to Lancaster, California to pick fat juicy cherries and sweet peaches from the old orchards. We?d make a day of it, hiking in ?The Devil?s Punchbowl¹?, having a burger at some roadside dive and driving home tired and happy, the smell of ripe fruit playing harmony with the music on the car radio. I remember one year Dad had to swerve when a car pulled in front of us and the trays of overripe strawberries flew through the air. When he eased to the shoulder of the road and yanked open the door on the old VW bus, it looked like someone had been horribly disemboweled on the back seat.

The next day we?d run out to the back porch, and he?d pull out the old hand-cranked wooden ice cream freezer, packing it with ice and rock salt shaken out of big paper sacks. All of us would take our turn, arms aching, trying to keep the cold metal cylinder spinning as the ingredients inside transformed into the magic of creamy, velvety ice cream. Gathering around as he removed the dasher, the cold cream would drip off and we?d all try to catch it with paper cups. While it set up in the freezer, Dad started the barbecue, and he and I would grind meat for hamburgers, carefully shaping them with a gentle touch. After they were eaten, fingers slick from buttery corn, cold bowls would be passed around the back porch, and there would be silence broken only by the slow scraping of spoons.

Dad was ahead of his time. All these years later I remember him making multiple batches, trying to get the flavors balanced just right. A man way ahead of his time, when the strawberries were especially good, he?d make freezer sorbet with cracked black pepper and a dash of vinegar.

Sitting with him in the kitchen while he made the batter, tasting, adjusting, and then seeing how the tastes changed again as it was frozen, I learned how difficult it is to adjust the recipe, especially as the flavor of ingredients changed intensity from year to year. He?d let me experiment with little batches, and I?d do my best to come up with new ideas. I wasn?t up to the task, as I always wanted to use my favorite foods; abalone, lobster and clam ice creams just don?t work.

Memories of those warm Sundays have drifted through my dreams ever since Salt & Straw Ice Cream opened on Alberta Street last year. Now with a second place on NW 23rd, lines are queuing at the door for good reason.

What sets Salt & Straw apart? It?s not only a step into the past when batters had a much higher percentage of milk-fat, but even more importantly, the balance achieved within the panoply of ingredients. Take a look at the current list of flavors:

Alberta Store

Pear and Blue Cheese
Sea Salt & Caramel Ribbons
Double Fold Vanilla
Chocolate and Gooey Brownies
Strawberry Balsamic and Black Pepper (be still my heart!)
Cinnamon Snickerdoodle
Coffee and Cocoa Nibs
Almond Brittle and Salted Ganache
Banana and Spicy Monkey Caramel and Walnuts

That?s just the regular flavors. Here are the seasonal:

Arbeguina Olive Oil
Dandelion Sorbet & Edible Wildflowers
Rhubarb & Toasted Anise Crumble
Honey Lavendar
Sweet Heat Apricot, Wheat Ale & Candied Peppers
Black Currant Sorbet

There is a lot that can go wrong with these combinations. I was a bit nervous about the pear and blue cheese, but once I tried it? crumbles of Rogue?s Crater Lake Blue and Truitt Brother?s pears? need I say more? Now I just throw caution to the wind and order a random flavor. Sweet heat Burnside Brewing Apricot Wheat Ale with candied Scotch bonnet peppers is a hot August afternoon on a cone. The classic combination of strawberries from Oregon Hill farms, honey balsamic from Honey Ridge Farms, and black pepper from Pohnpei made me flash back to a gelato I had in Rome. Cinnamon Snicker Doodle is made with Red Ape cinnamon from a spice company in Eugene which donates part of the proceeds to save the orangutans in Sumatra where the cinnamon is harvested ? no guilt ? I do it for the orangutans.

I could spend a lot more words discussing each flavor, but there isn?t much point, as these things are highly subjective. Just keep a few things in mind. The ice creams here aren?t the sugar bombs you may be used to; you?ll probably find this a good thing. If you try one and you don?t like it, don?t write off Salt & Straw. Try something else. Their most popular flavors are the Blue Cheese & Pear and the Salted Caramel. I thought I?d love the latter, but I didn?t, however the first made my toes curl in a good way. O Magazine raved about the Arbequina Olive Oil combination. While I appreciated the subtle grassy peppery flavor, a friend just thought it was greasy. Also, think about how different scoops will combine. Remember, this is high fat stuff, so it tends to be soft and flow together.

The staff is very patient, but do the people in front of me really need to try six flavors when the line behind them winds around the corner? I think not. I?d leap over the case and suffocate them, face down in Dandelion Sorbet.

Salt & Straw makes their own cones, and has floats, shakes, sundaes and a full line of breakfast pastries, cookies and desserts which are baked in-house. I have not tried them, as everyone knows that type of thing is fattening.

Single $3.75, double $5.75, Kid?s $2.75, Pints $8. Floats/shakes/sundaes $5 ? $6.75

2035 NE Alberta St., Portland ? 11am ? 11pm daily.

838 NW 23rd Ave, Portland ? 7am ? 11pm daily.

SaltandStraw.com

¹If you are really nice, someday I will tell you the story of me, a troop of Girl Scouts, and skinny-dipping at Devil?s Punchbowl.

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How to Get Back Your Email Subfolders on Samsung GALAXY Note on ICS

The aftermath after upgrading my Samsung GALAXY Note to Android 4.0.3 (Ice Cream Sandwich) is that I could not find the subfolders in my Exchange email account. It was frustrating to go through the options and no solution in site.

I thought I did a pretty good job to check through all settings. But I just could not find how I can call out the subfolders. BTW, subfolders means any folders under the Inbox.

If you have this problem after upgrading and your ICS version is Version 4.0.3, here is what you need to do.

Copy the settings of your email server.
Delete the email account.
Setup the email account again with the settings that you copied previously.

That is it. The subfolders will appear. Hope it helps. This solution is after I read this.

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Sunday, May 27, 2012

JPMorgan replaces prime brokerage head: source

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Sport Fitness ? Key Information on Sports Fitness Equipment | About ...

Various devices is accessible, especially for sports pursuits. As there are a amount of sports activities, there are as many diverse sorts of health equipments that are meant for sports. Choose the one particular that is proper for you and since there are so a lot of various health and fitness devices, it turns into quite perplexing for a person to decide on the right one. Go by the adhering to policies and you can surely stay away from problems although shopping for proper tools for sports.

Do not make haste while selecting fitness equipment, as you are likely to make a improper choice and repent later on on. Whilst getting this for sports you must have a certain reason to purchase distinct gear. Consequently set up your mind and make confident what your priorities are then you can go in advance.

You should be convinced about the need for the health and fitness gear for sports. The equipment should have all the capabilities that you wish for and fulfill all your wants or desires. The equipment ought to be demanding and taxing so as to make your perform out intriguing and satisfying. You will surely not use a device which you do not like.

Apply on different equipments just before buying 1 because this makes you common with the a single you want to purchase. If you try on specific equipment and have a good command over it then it becomes pretty straightforward to use it at property. A new one may sometimes turn into annoying if your work out is not turning out appropriate.

Up coming, make a observe on how considerably you would like to spend on equipment for sports activities. You would most probably really feel bound to use it since it turned out to be costly, resulting in an uninteresting and forceful work out. The best way to reduce your tensions is to correct a particular quantity and then go searching.

There are several outlets who supply minimal high quality health tools for reduced expense. Here you have to be thorough since eventually good quality is the most essential factor in health gear. Do not drop prey for the unbelievable offers that are normally presented in the shops, they are simply not value it.

Resale retailers are also a very good choice to purchase physical fitness equipment. If your spending budget is restricted, then resale shop is the response. They also offer discount rates on the equipments which are also great high quality goods with a range of merchandise to make your option straightforward. On-line stores can also be of great support for shopping for fitness devices.

Finally look at out for the space to place up your gear. Make a bodily examination and consult a medical professional for the suitable equipment just before buying.

Distinguished sporting establishments and distinguished athletic trainers like IFA Activity, Tennis 360, MPAC Sports activities, Maxtalent Worldwide Cricket Coaching Institute, First Health and fitness and numerous more will provide an fantastic knowledge for website visitors this summertime, ?

Sport Fitness School 2010: Session 2 (Part 2) ? Sport Fitness

Olympic Day slideshow from SFS Session two, 2010 ? www.athrec.mcmaster.ca/camps

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Gibbs: Bain is Romney's "thesis" for president, calls attacks fair (cbsnews)

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Saturday, May 26, 2012

Underland Express

Once you board the Underland Express, you'll wish you hadn't run away.

Owner:

Game Masters:

This topic is an Out Of Character part of the roleplay, ?Underland Express?. Anything posted here will also show up there.

Topic Tags:

Forum for completely Out of Character (OOC) discussion, based around whatever is happening In Character (IC). Discuss plans, storylines, and events; Recruit for your roleplaying game, or find a GM for your playergroup.
"Underland Express"

Please notify me if you wish to reserve a character. I will not accept your character if you do not reserve a spot. Please make sure you understand that these are regular human teenagers. They have no powers whatsoever. They can kick ass, but no god-modding. You can be good at something, but not perfect.

I want to make a Facebook account and name it Nobody so that when I like some post, it would say Nobody Likes This.

NasiaWords: Member for 1 years

Could I reserve a teenager? I'll have a form up soon.

TaniaSoulEater: Member for 0 years

Could I reserve a teenager as well?

Why in the world
Can't you see the things I see
The more I run into your arms
The more you run away from me

AvaLovelace: Member for 2 years

Post a reply

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